| Category | Funding IC | Project Number | Sub Project # | Project Title | PI Name | Org Name | State / Country | Amount |
|
Tuberous Sclerosis
|
NIDDK
|
5R01DK066366-05
|
|
IFN gamma and other modifiers of kidney disease in TSC
|
DABORA, SANDRA
|
BRIGHAM AND WOMEN'S HOSPITAL
|
MA
|
$255,476
|
|
Tuberous Sclerosis
|
NHLBI
|
5R01HL077514-03
|
|
Pathogenesis of Lymphangioleiomyomatosis
|
SCHUGER, LUCIA
|
WAYNE STATE UNIVERSITY
|
MI
|
$328,805
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA113793-03
|
|
Chemoprevention with mTOR & Farnesyltransferase Inhibitors
|
YOU, MING
|
WASHINGTON UNIVERSITY
|
MO
|
$261,976
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA073818-12
|
|
Molecular basis of Cell Growth Control by the TOR kinase
|
AVRUCH, JOSEPH
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$437,500
|
|
Tuberous Sclerosis
|
NINDS
|
5R01NS052707-02
|
|
Regulation of synapse growth by mTOR pathway
|
SABATINI, BERNARDO
|
HARVARD UNIVERSITY (MEDICAL SCHOOL)
|
MA
|
$370,781
|
|
Tuberous Sclerosis
|
NHLBI
|
5R01HL071106-06
|
|
Role of p70 S6 Kinase in Regulating LAM Cell Growth
|
KRYMSKAYA, VERA
|
UNIVERSITY OF PENNSYLVANIA
|
PA
|
$354,375
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA107164-04
|
|
Multicenter clinical trials for TSC & related disorders
|
DABORA, SANDRA
|
BRIGHAM AND WOMEN'S HOSPITAL
|
MA
|
$181,066
|
|
Tuberous Sclerosis
|
NIDCR
|
5R01DE017439-04
|
|
mTOR SIGNALING: A NOVEL MECHANISM OF WNT'S ANABOLIC EFFECTS ON BONE
|
OUYANG, HONGJIAO
|
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
|
PA
|
$345,514
|
|
Tuberous Sclerosis
|
NIDDK
|
2R01DK053194-06A2
|
|
Rho GTPases and Actin Cytoskeletal Function in Renal Ischemia
|
ATKINSON, SIMON
|
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
|
IN
|
$316,597
|
|
Tuberous Sclerosis
|
NHLBI
|
5R01HL081147-03
|
|
Regulation of Estrogen Signaling by Tuberin and Rheb
|
HENSKE, ELIZABETH
|
FOX CHASE CANCER CENTER
|
PA
|
$415,103
|
|
Tuberous Sclerosis
|
NIDDK
|
5R01DK051052-12
|
|
Mechanisms of Renal Tumorigenesis in Tuberous Sclerosis
|
HENSKE, ELIZABETH
|
FOX CHASE CANCER CENTER
|
PA
|
$308,251
|
|
Tuberous Sclerosis
|
NIDDK
|
5F32DK076443-02
|
|
Roles of TSC1 TDC2 and Rheb in renal cyst pathogenesis
|
HARTMAN, TIFFINEY
|
FOX CHASE CANCER CENTER
|
PA
|
$50,428
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA102662-05
|
|
In Vivo Studies of TSC-Related Tumorigenesis
|
YEUNG, RAYMOND
|
UNIVERSITY OF WASHINGTON
|
WA
|
$294,676
|
|
Tuberous Sclerosis
|
NINDS
|
5R21NS056878-02
|
|
Interaction Between DJ-1 and TSC1-TSC2/TOR Signaling in Cell Survival
|
LU, BINGWEI
|
PALO ALTO INSTITUTE FOR RES & EDU, INC.
|
CA
|
$183,750
|
|
Tuberous Sclerosis
|
NIDDK
|
5R01DK015658-37
|
|
Regulation of Skeletal Muscle Metabolism
|
JEFFERSON, LEONARD
|
PENNSYLVANIA STATE UNIV HERSHEY MED CTR
|
PA
|
$348,516
|
|
Tuberous Sclerosis
|
NINDS
|
5R37NS031535-15
|
|
Tuberous Sclerosis: Mutations and Murine Models
|
KWIATKOWSKI, DAVID
|
BRIGHAM AND WOMEN'S HOSPITAL
|
MA
|
$338,848
|
|
Tuberous Sclerosis
|
NINDS
|
5K08NS051843-04
|
|
VEGF regulation by the TSC2 tumor suppressor
|
BRUGAROLAS, JAMES
|
UNIVERSITY OF TEXAS SW MED CTR/DALLAS
|
TX
|
$172,976
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA122617-03
|
|
Pathologic and therapeutic implications of Akt attenuation in TSC cells and tumor
|
MANNING, BRENDAN
|
HARVARD UNIVERSITY (SCH OF PUBLIC HLTH)
|
MA
|
$255,599
|
|
Tuberous Sclerosis
|
NINDS
|
5R01NS058230-03
|
|
Growth regulatory targets of the Tuberous Sclerosis Complex
|
EDGAR, BRUCE
|
FRED HUTCHINSON CANCER RESEARCH CENTER
|
WA
|
$377,962
|
|
Tuberous Sclerosis
|
NIDDK
|
1R01DK081009-01
|
|
The In Vivo Role of JNK-1 and IRS-1 Ser307 Phosphorylation In Development of Insu
|
OZCAN, UMUT
|
CHILDREN'S HOSPITAL BOSTON
|
MA
|
$338,000
|
|
Tuberous Sclerosis
|
NINDS
|
5R01NS058956-02
|
|
Role of TSC Proteins in Neuronal Polarity and Axon Guidance
|
SAHIN, MUSTAFA
|
CHILDREN'S HOSPITAL BOSTON
|
MA
|
$369,688
|
|
Tuberous Sclerosis
|
NINDS
|
5K08NS050484-02
|
|
The Role of TSC Genes During Brain Development
|
ESS, KEVIN
|
VANDERBILT UNIVERSITY
|
TN
|
$165,629
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA129814-02
|
|
Elucidating the role of the mTOR pathway in NF1-related tumorigenesis
|
CICHOWSKI, KAREN
|
BRIGHAM AND WOMEN'S HOSPITAL
|
MA
|
$300,291
|
|
Tuberous Sclerosis
|
NIGMS
|
5R01GM070537-04
|
|
Function of the Small GTPase Rheb in Cell Growth
|
PAN, DUOJIA
|
JOHNS HOPKINS UNIVERSITY
|
MD
|
$248,803
|
|
Tuberous Sclerosis
|
NINDS
|
2P01NS024279-20A2
|
0014
|
Molecular Genetics Of Meningioma and Neurofibromatosis Related Disorders
|
GUSELLA, JAMES
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$379,828
|
|
Tuberous Sclerosis
|
NINDS
|
2P01NS024279-20A2
|
0015
|
Mouse Brain Models of Tuberous Sclerosis
|
KWIATKOWSKI, DAVID
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$312,537
|
|
Tuberous Sclerosis
|
NINDS
|
2P01NS024279-20A2
|
0016
|
Vector Query and Therapy For TSC and NF2 Lesions
|
BREAKEFIELD, XANDRA
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$291,359
|
|
Tuberous Sclerosis
|
NINDS
|
2P01NS024279-20A2
|
9009
|
CLINICAL CORE
|
THIELE, ELIZABETH
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$164,880
|
|
Tuberous Sclerosis
|
NINDS
|
2P01NS024279-20A2
|
9010
|
NEUROPATHOLOGY CORE
|
STEMMER-RACHAMIMOV, ANAT
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$189,907
|
|
Tuberous Sclerosis
|
NCI
|
1R01CA129821-01A1
|
|
The Role of FKBP38 in tumorigenesis associated with Tsc deficiency
|
JIANG, YU
|
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
|
PA
|
$281,526
|
|
Tuberous Sclerosis
|
NINDS
|
2R01NS045021-05A1
|
|
Structural consequences of TSC gene mutations in brain
|
CRINO, PETER
|
UNIVERSITY OF PENNSYLVANIA
|
PA
|
$310,078
|
|
Tuberous Sclerosis
|
NCI
|
1R01CA129105-01A1
|
|
Cell Growth Signaling in Cancer Development
|
SABATINI, DAVID
|
WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
|
MA
|
$399,870
|
|
Tuberous Sclerosis
|
NIDDK
|
5R01DK078043-02
|
|
Regulation of the mTOR pathway in polycystic kidney disease
|
WEIMBS, THOMAS
|
UNIVERSITY OF CALIFORNIA SANTA BARBARA
|
CA
|
$269,204
|
|
Tuberous Sclerosis
|
NINDS
|
5K12NS001692-10
|
|
Neurological Sciences Academic Development Awards
|
FERRIERO, DONNA
|
UNIVERSITY OF CALIFORNIA SAN FRANCISCO
|
CA
|
$563,443
|
|
Tuberous Sclerosis
|
NINDS
|
5R01NS053588-02
|
|
Tuberous sclerosis complex in memory formation
|
DASH, PRAMOD
|
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
|
TX
|
$324,844
|
|
Tuberous Sclerosis
|
NIAMS
|
5R01AR050727-04
|
|
Skin Manifestations of Tuberous Sclerosis
|
ARBISER, JACK
|
EMORY UNIVERSITY
|
GA
|
$218,943
|
|
Tuberous Sclerosis
|
NINDS
|
5R01NS056872-03
|
|
Mechanisms of Brain Dysfunction in Tuberous Sclerosis
|
WONG, MICHAEL
|
WASHINGTON UNIVERSITY
|
MO
|
$232,458
|
|
Tuberous Sclerosis
|
NIMH
|
5R21MH079213-02
|
|
Genes that deregulate mTOR signaling as candidates for autism spectrum disorders
|
RAMESH, VIJAYA
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$196,875
|
|
Tuberous Sclerosis
|
NIDDK
|
5R01DK074835-02
|
|
Mammalian target of rapamycin (mTOR) signaling in polycystic kidney disease (PKD)
|
EDELSTEIN, CHARLES
|
UNIVERSITY OF COLORADO DENVER
|
CO
|
$296,368
|
|
Tuberous Sclerosis
|
NCI
|
5K22CA124517-02
|
|
Study of mTOR Regulation by Rheb Using Deuterium Exchange Mass Spectrometry
|
CASTEEL, DARREN
|
UNIVERSITY OF CALIFORNIA SAN DIEGO
|
CA
|
$140,862
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA122589-02
|
|
Function and mechanism of REDD1 signaling to TSC1/2 and mTORC1
|
ELLISEN, LEIF
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$329,650
|
|
Tuberous Sclerosis
|
NCI
|
5R01CA125436-02
|
|
mTOR-containing Protein Complexes in the Pathogenesis of Tuberous Sclerosis
|
KRISTOF, ARNOLD
|
MCGILL UNIVERSITY
|
CANADA
|
$177,240
|
|
Tuberous Sclerosis
|
NINDS
|
5R01NS060804-02
|
|
Mouse Models of the Neuropathology of Tuberous Sclerosis Complex
|
GAMBELLO, MICHAEL
|
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
|
TX
|
$258,136
|
|
Tuberous Sclerosis
|
NCI
|
1R21CA135057-01
|
|
The role of FOXO transcriptional factors in TSC-mediated tumorigenesis
|
DEPINHO, RONALD
|
DANA-FARBER CANCER INSTITUTE
|
MA
|
$171,000
|
|
Tuberous Sclerosis
|
NCI
|
2R01CA077882-10A2
|
|
Pathogenesis of TSC2-Related Tumors
|
YEUNG, RAYMOND
|
UNIVERSITY OF WASHINGTON
|
WA
|
$355,095
|
|
Tuberous Sclerosis
|
NHLBI
|
1R01HL090829-01A1
|
|
The Role of TSC2 and Rho GTPases in LAM
|
KRYMSKAYA, VERA
|
UNIVERSITY OF PENNSYLVANIA
|
PA
|
$393,750
|
|
Tuberous Sclerosis
|
NEI
|
1R01EY018213-01A2
|
|
Toward mechanism- and gene-based therapies for retinal degeneration
|
TSANG, STEPHEN
|
COLUMBIA UNIVERSITY HEALTH SCIENCES
|
NY
|
$320,600
|
|
Tuberous Sclerosis
|
NINDS
|
1R21NS060025-01A1
|
|
Allelic Expression Imbalance in Tuberous Sclerosis Complex
|
NARAYANAN, VINODH
|
ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER
|
AZ
|
$221,598
|
|
Tuberous Sclerosis
|
NHLBI
|
1R13HL093774-01
|
|
2008 LAM Foundation International Research Conference
|
MCCORMACK, FRANCIS
|
UNIVERSITY OF CINCINNATI
|
OH
|
$20,000
|
|
Tuberous Sclerosis
|
NCI
|
1R03CA132103-01A1
|
|
Mouse Model of Pancreatic Tumorigenesis with Dysregulation of mTOR
|
FRAZIER, MARSHA
|
UNIVERSITY OF TEXAS MD ANDERSON CAN CTR
|
TX
|
$77,000
|
|
Tuberous Sclerosis
|
NINDS
|
1P50NS057531-01A2
|
0001
|
Bench to Bedside: Signaling
|
THOMAS, GEORGE
|
CHILDREN'S HOSPITAL MED CTR (CINCINNATI)
|
OH
|
$741,181
|
|
Tuberous Sclerosis
|
NCI
|
1R01CA129387-01A2
|
|
Regulation of the mTOR Pathway by Hypoxia and the REDD1 Protein
|
BRUGAROLAS, JAMES
|
UNIVERSITY OF TEXAS SW MED CTR/DALLAS
|
TX
|
$319,260
|
|
Tuberous Sclerosis
|
NCI
|
5P01CA116676-03
|
0001
|
Modulation of the mTOR Pathway for Lung Cancer Treatment
|
KHURI, FADLO
|
EMORY UNIVERSITY
|
GA
|
$339,926
|
|
Tuberous Sclerosis
|
NCRR
|
5M01RR000188-44
|
7797
|
THE ROLE OF THE RETT GENE, CHROMOSOME 15Q11-Q13, OTHER GENES, AND EPIGENETICS
|
BEAUDET, ARTHUR
|
BAYLOR COLLEGE OF MEDICINE
|
TX
|
$19,631
|
|
Tuberous Sclerosis
|
NCRR
|
5M01RR008084-15
|
7912
|
CLINICAL TRIAL: RAD001 THERAPY OF ANGIOMYOLIPOMATA IN PATIENTS WITH TSC
|
BISSLER, JOHN
|
CHILDREN'S HOSPITAL MED CTR (CINCINNATI)
|
OH
|
$520
|
|
Tuberous Sclerosis
|
NCRR
|
5P41RR000862-35
|
8330
|
FOLLOWING THE FATE OF HCMV GENE PRODUCTS IN HOST CELLS
|
SHENK, THOMAS
|
ROCKEFELLER UNIVERSITY
|
NY
|
$44,285
|
|
Tuberous Sclerosis
|
NCRR
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$68,395
|
|
Tuberous Sclerosis
|
NEI
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$13,983
|
|
Tuberous Sclerosis
|
NHLBI
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$12,585
|
|
Tuberous Sclerosis
|
NIAID
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$13,983
|
|
Tuberous Sclerosis
|
NIAMS
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$2,797
|
|
Tuberous Sclerosis
|
NIDDK
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$4,552
|
|
Tuberous Sclerosis
|
OD
|
2U42RR006042-18
|
6868
|
LYMPHANGIOLEIOMYOMATOSIS (LAM) REGISTRY
|
LONSDALE, JOHN
|
NATIONAL DISEASE RESEARCH INTERCHANGE
|
PA
|
$18,714
|
|
Tuberous Sclerosis
|
NCRR
|
3U54RR019498-05S1
|
6960
|
RARE LUNG DISEASE CLINICAL RESEARCH NETWORK
|
TRAPNELL, BRUCE
|
CHILDREN'S HOSPITAL MED CTR (CINCINNATI)
|
OH
|
$1
|
|
Tuberous Sclerosis
|
OD
|
3U54RR019498-05S1
|
6960
|
RARE LUNG DISEASE CLINICAL RESEARCH NETWORK
|
TRAPNELL, BRUCE
|
CHILDREN'S HOSPITAL MED CTR (CINCINNATI)
|
OH
|
$655,547
|
|
Tuberous Sclerosis
|
NCI
|
5P01CA120964-02
|
0001
|
Tuberous Sclerosis-Pathway and Pathogenesis
|
KWIATKOWSKI, DAVID
|
BRIGHAM AND WOMEN'S HOSPITAL
|
MA
|
$430,816
|
|
Tuberous Sclerosis
|
NCI
|
5P01CA120964-02
|
0003
|
Dissection of Tsc1/Tsc2/Tor/S6K Signaling in Drosophila
|
PERRIMON, NORBERT
|
HARVARD UNIVERSITY (MEDICAL SCHOOL)
|
MA
|
$360,185
|
|
Tuberous Sclerosis
|
NCI
|
5P01CA120964-02
|
9002
|
Mass Spectrometry Core
|
CANTLEY, LEWIS
|
BETH ISRAEL DEACONESS MEDICAL CENTER
|
MA
|
$162,204
|
|
Tuberous Sclerosis
|
NCI
|
5P01CA120964-02
|
9003
|
Human Pathology and Immunohistochemistry Core
|
WU, CHIN-LEE
|
MASSACHUSETTS GENERAL HOSPITAL
|
MA
|
$152,295
|
|
Tuberous Sclerosis
|
NCI
|
1Z01BC009264-25
|
|
Cytokine Regulation of Normal and Neoplastic Hematopoietic Cell Growth
|
RUSCETTI, FRANCIS
|
NIH
|
|
$762,443
|
|
Tuberous Sclerosis
|
NHLBI
|
1Z01HL002541-13
|
|
Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)
|
MOSS, JOEL
|
NIH
|
|
$2,100,780
|
